Peptide Therapy

AOD 9604 is a modified form of amino acids 176-191 of the GH polypeptide, which was designed to help people burn fat, especially in the abdomen.

Potential Benefits: Weight loss

AOD 9604 has no adverse effects on blood sugar or growth.

AOD 9604 possesses many other regenerative properties associated with growth hormone.

Current trials are underway to show the application of AOD 9604 in osteoarthritis, hypercholesterolemia, bone + cartilage repair.

Common Protocol: AOD 9604 is often taken topically as a cream or sublingual troche. Typical dose is 200-600mcg daily in combination with a low carb/low calorie diet plan.

BPC-157 is a pentadecapeptide made up of 15 amino acids.

Potential Benefits: Experiments have shown that it heightens the healing of many different types of tissues, including: tendon, muscle, nervous system, + is superior at healing damaged ligaments.

Those who suffer from pain due to sprains, tears, + tissue damage may benefit from BPC 157 as it can increase blood flow to the injured sites.

BPC-157 may protect organs, prevent stomach ulcers, and heal skin burns.

Common Protocol: Often based on body weight using 2mcg/kg to as much as 10mcg/kg twice daily.

• Doses commonly range from 200mcg to 1mg once-twice daily.

• If used twice daily, intramuscular injection as close to the injury as possible or via subcutaneously for systemic purposes. Oral supplementation is more for gastrointestinal support.

• Used for 2-4 weeks before discontinuing for 2 weeks, then restarting therapy as needed.

PT-141 was developed from the peptide Melanotan 2, which is a synthetically produced variant of a peptide hormone naturally produced
in the body that stimulates melanogenesis.

PT-141 can help women ‘s libido + to achieve orgasm + male erectile dysfunction or impotence. Studies have shown that PT-141 does not act on the vascular system, but may increase sexual desire through the nervous system.

It works in 80% of men who don’t respond to PDE5 inhibitors + most now use it as first-line therapy.

Side effects include nausea, flushing, + headache.

Common Protocol via Nasal Spray:
1-2mg/dose or 1-2 sprays per nostril, at least one hour before the desired effect. It can be increased if results aren’t seen, but side effects such as nausea will be dose-dependent. Recommended to use no more than two times per week.

Ipamorelin Acetate is a Growth Hormone Releasing Peptide
(GHRP) that assists in increasing the amount of growth hormone
released. The four most common GHRPs are Ipamorelin, GHRP-2, GHRP-6, and Hexarelin – in order of strength.

Potential Benefits: Promotes slow wave sleep, improves memory retention, stimulates muscle growth, aids in fat loss + lean muscle.

Common Protocol: Ipamorelin stacked with Sermorelin + Theanine as sublingual tablet 180mcg taken before bed or at least 30 minutes away from food. Those with a higher BMI or high estrogen levels may require larger doses.

Suggested Add-on: AOD 9604 for enhanced weight loss

Ibutamoren is a non-peptide growth
hormone secretagogue + mimics the growth hormone stimulating action of ghrelin (which can increase appetite). Clinically, it has been demonstrated to increase endogenous release of growth hormone (GH) as well as insulin-
like growth factor 1 (IGF-1) without the adverse increase of prolactin or cortisol often seen with GHRPs. Additionally, increases in lean body mass can be achieved while lowering LDL cholesterol.

Potential Benefits: Increase both muscle mass + bone mineral density, making it a promising therapy for frailty + osteoporosis in the elderly. Decrease fat mass, faster healing, firmer, healthier skin + hair, improved sleep quality, + anti-aging.

Common Protocol: Baseline IGF-1 blood test + every 30 days during treatment duration of 2-3 months. 10-25mg tablet at bedtime daily.

DIHEXA is a nootropic peptide variant derived from angiotensin IV.

Potential Benefits: Improves cognitive
function as shown in animal models of disease such as Alzheimer’s. DIHEXA was found to be seven orders of
magnitude more potent than brain-derived neurotrophic factor + may help brain + nerve repair in neurological disease.

Common Protocol: For the cream, 2-4 clicks to inner forearm daily.

For capsules, 10-45 milligrams daily.

GHRP-2 is a synthetically made growth hormone secretagogue, a peptide that stimulates the body to increase natural production of growth hormone in two ways. First, the peptide enhances the natural growth hormone releasing signal. Second, it suppresses the hormone Somatostatin, also known as growth hormone inhibiting hormone (GHIH).

Potential Benefits: GHRP-2 has been structurally modified to limit the appetite increasing effects of ghrelin.
Because GHRP-2 stimulates the body to produce GH, there is no shutdown of natural growth hormone production as occurs with synthetic HGH administration. GHRP-2 causes GH secretion in a way that more closely resembles natural release patterns, rather than being constantly elevated. This results in fewer side effects compared with synthetic HGH.

Common Protocol: Blood IGF-1 taken foundationally + every month thereafter during treatment for up to 6 months. Sermorelin taken at bedtime (which enhances the release of GH into the bloodstream) + 2mg sublingual GHRP2 taken first thing AM (which increases production of GH), when combined can offer a 5-fold efficacy. For best results, it is recommended to avoid eating at least 1 hour before + after administering GHRP-2.

Suggested Add-On: Testosterone

GHK-Cu (glycyl-l-histidyl-l-lysine) is a small, naturally occurring tri-peptide present in human plasma that also can be released from tissues in case of an injury.

Potential Benefits: Studies have shown that copper peptide promotes the production of collagen + elastin to firm + plump aging skin. It also acts as an antioxidant + promotes production of glycosaminoglycans (such as hyaluronic acid). Reduces fine lines, depth of wrinkles, smooths rough skin, reduces photo-damaged, mottled hyperpigmentation, skin spots + lesions. Increases hair growth + thickness, + enlarges hair follicle size.

Common Protocol: As a cream or topical solution, 1-2mg can be applied daily to desired areas of treatment. As a scalp foam, 4-6mg nightly.

KPV contains the active bioregulator fragment of α-melanocyte stimulating hormone (α-MSH), which is considered to be one of the body’s most potent regulators of normal immune balance and mast cell system stimulation. It can treat a wide variety of inflammatory conditions, including Inflammatory Bowel Diseases (IBD) Ulcerative Colitis and Crohn’s Disease.
It can improve skin health and is used in healing wounds & injuries.

SEMAX (MEHFPGP) is the analogue
of ACTH (4-10) that has prolonged neurotropic activity. This has historically been used in people with brain circulation dysfunction.

Potential Benefits: Semax primes the brain for action, which can lead to a reduction of behaviors like avoidance + procrastination. Semax may also induce a controlled state of mental stress, which can optimize of brain function. It may help with ADHD, high intensity exercise, prevent oxidative damage, improve blood circulation, reduce anxiety + depression, + ease pain.

Common Protocol: 750mcg Nasal Spray once daily x 10 days.

Sermorelin is another powerful peptide used to help augment human growth hormone (HGH) production. Just like ipamorelin, sermorelin is a growth hormone peptide, but it works differently in the body by stimulating GHRH instead of ghrelin. This stimulates growth hormone release from the pituitary gland. Benefits of sermorelin therapy include decreased body fat, increased endurance and strength, increased lean muscle mass, and improved sleep.

Thymogen alpha-1’s primary role is to improve immune system function by stimulating and coordinating various molecules and pathways in the immune system. Through this, it may help with a variety of conditions, including the following, inflammation reduction, Type 1 Diabetes, pancreatitis.